Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 20/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9378167 | 0.90 | PTAFR (1.00) | PTAFR | |
| Hydrochloric Acid SCHEMBL9378428 | 0.90 | PTAFR (0.98) | PTAFR | |
| SCHEMBL9380501 | 0.88 | PTAFR (1.00) | PTAFR | |
| SCHEMBL9384759 | 0.85 | PTAFR (1.00) | PTAFR | |
| SCHEMBL9043481 | 0.83 | PTAFR (0.82) | PTAFR | |
| SCHEMBL9383295 | 0.82 | PTAFR (1.00) | PTAFR | |
| SCHEMBL9379408 | 0.82 | PTAFR (1.00) | PTAFR | |
| SCHEMBL27314358 | 0.82 | PTAFR (0.78) | PTAFR | |
| SCHEMBL9379443 | 0.82 | PTAFR (1.00) | PTAFR | |
| SCHEMBL10588326 | 0.81 | PTAFR (0.77) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320992-B1 | Triazolodiazepine derivatives | HOFFMANN LA ROCHE (CH) | 1994-07-27 | — | — | EP | disclosed |
| US-4959361-A | Triazolo(4,3-A)(1,4)benzodiazepines and thieno (3,2-F)(1,2,4)triazolo(4,3-A)(1,4)diazepine compounds which have useful activity as platelet activating factor (PAF) antagonists | HOFFMANN-LA ROCHE INC. (US) | 1990-09-25 | — | — | US | disclosed |