Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CCR1 | P32246 | 2/20 | 0.45 |
| ▸ | CCR5 | P51681 | 2/20 | 0.45 |
| ▸ | CCR8 | P51685 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.45 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4560363 | 0.85 | MKNK1 (0.50) | KDM4ECYP1A2BLMMKNK1MKNK2 | |
| SCHEMBL30661057 | 0.84 | KDM4E (0.46) | GRM5TGFBR1KDM4ELMNACCR1 | |
| SCHEMBL9405123 | 0.84 | KDM4E (0.53) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL22616671 | 0.84 | KDM4E (0.46) | GRM5TGFBR1KDM4ELMNACCR1 | |
| Oxalic Acid SCHEMBL30661054 | 0.83 | GRM5 (0.41) | GRM5TGFBR1KDM4ELMNACCR1 | |
| Acetic Acid SCHEMBL30661059 | 0.82 | BRD4 (0.43) | GRM5TGFBR1KDM4ELMNACCR1 | |
| Hydrochloric Acid SCHEMBL30661064 | 0.82 | KDM4E (0.45) | GRM5TGFBR1KDM4ELMNACCR1 | |
| Bromide SCHEMBL30661063 | 0.82 | KDM4E (0.45) | GRM5TGFBR1KDM4ELMNACCR1 | |
| Hydrochloric Acid SCHEMBL30661066 | 0.82 | KDM4E (0.45) | GRM5TGFBR1KDM4ELMNACCR1 | |
| SCHEMBL30665069 | 0.81 | CA1 (0.42) | GRM5TGFBR1KDM4ELMNACCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389189-B1 | Diazepine antiallergy agents | PFIZER LTD (GB) | 1994-05-18 | — | — | EP | claimed |
| US-5008263-A | Platelet activating factor antagonists; antiallergens; antiinflammatory agents | PFIZER INC. (US) | 1991-04-16 | — | — | US | claimed |
| EP-0389189-A2 | Diazepine antiallergy agents | Pfizer Limited (GB) | 1990-09-26 | — | — | EP | claimed |
| CN-107108568-B | Pesticidally active amide heterocyclic derivatives with sulphur containing substituents | 先正达参股股份有限公司 | 2021-08-10 | — | — | CN | disclosed |
| EP-0389189-B1 | Diazepine antiallergy agents | PFIZER LTD (GB) | 1994-05-18 | — | — | EP | disclosed |
| US-5008263-A | Platelet activating factor antagonists; antiallergens; antiinflammatory agents | PFIZER INC. (US) | 1991-04-16 | — | — | US | disclosed |
| EP-0389189-A2 | Diazepine antiallergy agents | Pfizer Limited (GB) | 1990-09-26 | — | — | EP | disclosed |