Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.50 |
| ▸ | CES2 | O00748 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94904 | 0.97 | — | — | |
| SCHEMBL3730209 | 0.95 | CES1 (0.50) | CES1CES2MAPTKMT2AALDH1A1 | |
| SCHEMBL9051919 | 0.90 | KMT2A (0.64) | CES1CES2MAPTKMT2AALDH1A1 | |
| SCHEMBL9051186 | 0.90 | KMT2A (0.64) | CES1CES2MAPTKMT2AALDH1A1 | |
| SCHEMBL29026111 | 0.90 | KMT2A (0.64) | CES1CES2MAPTKMT2AALDH1A1 | |
| SCHEMBL1022555 | 0.90 | KMT2A (0.62) | CES1CES2MAPTKMT2AALDH1A1 | |
| Ethylene Glycol SCHEMBL28684007 | 0.89 | CES1 (0.55) | CES1CES2MAPTKMT2AALDH1A1 | |
| SCHEMBL11872988 | 0.89 | CES1 (0.61) | CES1CES2MAPTKMT2AALDH1A1 | |
| SCHEMBL1771855 | 0.89 | CES1 (0.61) | CES1CES2MAPTKMT2AALDH1A1 | |
| SCHEMBL25405661 | 0.87 | KMT2A (0.67) | CES1CES2MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994002540-A1 | HIGHLY FILLED POLYMERIC COMPOSITIONS | LUCEY MICHAEL F (US) | 1994-02-03 | — | — | WO | disclosed |