Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.49 |
| ▸ | TTR | P02766 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | UNG | P13051 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | P4HB | P07237 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9385684 | 1.00 | KAT8 (0.49) | KAT8TTRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9334957 | 0.86 | KAT8 (0.48) | KAT8TTRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9389070 | 0.86 | KAT8 (0.48) | KAT8TTRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9642572 | 0.85 | MEN1 (0.52) | KAT8TTRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9642574 | 0.85 | MEN1 (0.52) | KAT8TTRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9334994 | 0.83 | KAT8 (0.53) | KAT8NPC1RAB9ASMN1; SMN2DYRK1A | |
| SCHEMBL9335002 | 0.83 | KAT8 (0.53) | KAT8NPC1RAB9ASMN1; SMN2DYRK1A | |
| SCHEMBL9335180 | 0.80 | KAT8 (0.50) | KAT8NPC1RAB9ASMN1; SMN2DYRK1A | |
| SCHEMBL9335185 | 0.80 | KAT8 (0.50) | KAT8NPC1RAB9ASMN1; SMN2DYRK1A | |
| SCHEMBL9338937 | 0.80 | KAT8 (0.50) | KAT8NPC1RAB9ASMN1; SMN2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533695-B1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY | PFIZER (US) | 1994-10-05 | — | — | EP | disclosed |
| WO-1991017163-A1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY | PFIZER INC. (US) | 1991-11-14 | — | — | WO | disclosed |