SCHEMBL93858

SCHEMBL93858

O=C(O)c1cc2ccccc2s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 1.00
HDAC1 Q13547 2/20 0.67
HDAC3 O15379 1/20 0.67
HDAC4 P56524 1/20 0.67
HDAC7 Q8WUI4 1/20 0.67
HDAC2 Q92769 1/20 0.67
HDAC10 Q969S8 1/20 0.67
HDAC11 Q96DB2 1/20 0.67
HDAC8 Q9BY41 1/20 0.67
HDAC6 Q9UBN7 1/20 0.67
HDAC9 Q9UKV0 1/20 0.67
HDAC5 Q9UQL6 1/20 0.67
CA12 O43570 1/20 0.59
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
CA4 P22748 1/20 0.59
CA5A P35218 1/20 0.59
CA7 P43166 1/20 0.59
CA9 Q16790 1/20 0.59
CA14 Q9ULX7 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29438783 1.00 BCL2L1 (1.00) BCL2L1HDAC1HDAC3HDAC4HDAC7
Hydrochloric Acid SCHEMBL443833 0.98 BCL2L1 (0.96) BCL2L1HDAC1HDAC3HDAC4HDAC7
SCHEMBL7785404 0.91 BCL2L1 (0.83) BCL2L1HDAC1HDAC3HDAC4HDAC7
Beta-Naphtoic Acid SCHEMBL27589159 0.87 BCL2L1 (0.75) BCL2L1HDAC1HDAC3HDAC4HDAC7
SCHEMBL31057044 0.86 BCL2L1 (0.76) BCL2L1HDAC1HDAC3HDAC4HDAC7
SCHEMBL7209477 0.85 BCL2L1 (0.74) BCL2L1HDAC1HDAC3HDAC4HDAC7
SCHEMBL31356465 0.85 BCL2L1 (0.74) BCL2L1HDAC1HDAC3HDAC4HDAC7
SCHEMBL6321234 0.85 BCL2L1 (0.74) BCL2L1HDAC1HDAC3HDAC4HDAC7
SCHEMBL7639982 0.84 BCL2L1 (0.72) BCL2L1HDAC1HDAC3HDAC4HDAC7
Benzofuran SCHEMBL28562639 0.84 BCL2L1 (0.71) BCL2L1HDAC1HDAC3HDAC4HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2064 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4646404-A1 PEPTIDE-HISTIDINAL CONJUGATES AS AN ANTI-MALARIAL AGENTS Council of Scientific & Industrial Research (IN) 2025-11-12 EP claimed
CN-119823008-A Preparation method of 4-methylsulfonyl phenylacetic acid 浙江东亚药业股份有限公司 2025-04-15 CN claimed
CN-118756140-A For CO2Laser direct drilling pretreatment additive, preparation method and application thereof 昆山市板明电子科技有限公司 2024-10-11 CN claimed
WO-2024147153-A1 PEPTIDE-HISTIDINAL CONJUGATES AS AN ANTI-MALARIAL AGENTS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2024-07-11 WO claimed
US-20240025884-A1 COMPOUNDS AS GCN2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF DONG-A ST CO., LTD. (KR) 2024-01-25 US claimed
CN-117304178-A Polymerizable aqueous photoinitiator and preparation method and application thereof 佛山市新量子环保材料有限公司 2023-12-29 CN claimed
US-20230242572-A1 a-CARBONYL ALKENYL ESTER PREPARATION METHOD THEREFOR AND APPLICATION THEREOF JIANGXI NORMAL UNIVERSITY (CN) 2023-08-03 US claimed
CN-111057093-B Tricyclohexyltin benzothiophene-2-formate complex and preparation method and application thereof 衡阳师范学院 2023-06-23 CN claimed
CN-111057094-B Tris (2-methyl-2-phenylpropyl) tin benzothiophene-2-formate complex and preparation method and application thereof 衡阳师范学院 2023-06-23 CN claimed
CN-111841896-B Benzo-heterocycle hydroximic acid collecting agent and preparation method and application thereof 武汉工程大学 2022-10-18 CN claimed
US-5965749-A Process for synthesizing substituted 2-benzo [b]thiophenecarboxylic acids and salts thereof UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-10-12 US claimed
WO-1999047510-A2 PROCESS FOR SYNTHESIZING SUBSTITUTED 2-BENZO[b] THIOPHENE CARBOXYLIC ACIDS AND SALTS THEREOF UNIROYAL CHEMICAL COMPANY, INC. (US) 1999-09-23 WO claimed
EP-0885893-A1 NOVEL TETRAHYDRONAPHTHOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME MEIJI SEIKA KAISHA LTD. (JP) 1998-12-23 EP claimed
EP-0572712-B1 Processes for producing 2-substituted benzo(beta)thiophene SUMITOMO SEIKA CHEMICALS (JP) 1998-01-21 EP claimed
US-5391567-A Oral administeration MACROCHEM CORPORATION (US) 1995-02-21 US claimed
US-5344941-A Treatment of osteoporosis MACROCHEM CORPORATION 1994-09-06 US claimed
US-5298630-A Reacting 2-alkylthiobenzaldehyde derivative with halo compound SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1994-03-29 US claimed
EP-0572712-A2 Processes for producing 2-substituted benzo(beta)thiophene SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1993-12-08 EP claimed
EP-0259168-B1 NEW WATER-SOLUBLE SALTS OF THIONAPTHENE-2-CARBOXYLIC ACID Macrochem Corporation (US) 1991-12-11 EP claimed
EP-0259168-A1 New water-soluble salts of thionapthene-2-carboxylic acid Macrochem Corporation (US) 1988-03-09 EP claimed