Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9386195 | 0.90 | PTAFR (0.59) | PTAFRSIGMAR1TBXAS1HRH3 | |
| SCHEMBL9388143 | 0.88 | PTAFR (0.59) | PTAFRSIGMAR1TBXAS1 | |
| SCHEMBL9391113 | 0.84 | PTAFR (0.56) | PTAFRSIGMAR1 | |
| SCHEMBL9387174 | 0.82 | PTAFR (0.53) | PTAFRSIGMAR1 | |
| SCHEMBL9387250 | 0.81 | PTAFR (0.62) | PTAFRTBXAS1HRH3KDM4EALDH1A1 | |
| SCHEMBL9387180 | 0.81 | PTAFR (0.62) | PTAFRTBXAS1HRH3KDM4EALDH1A1 | |
| SCHEMBL9390517 | 0.81 | PTAFR (0.62) | PTAFRTBXAS1HRH3KDM4EALDH1A1 | |
| SCHEMBL9391107 | 0.80 | PTAFR (0.57) | PTAFRSIGMAR1TBXAS1KDM4EALDH1A1 | |
| SCHEMBL9386186 | 0.80 | PTAFR (0.62) | PTAFRTBXAS1KDM4EALDH1A1 | |
| SCHEMBL9388172 | 0.78 | PTAFR (0.55) | PTAFRSIGMAR1TBXAS1HRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994001434-A1 | BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES AS PAF ANTAGONISTS | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1994-01-20 | — | — | WO | disclosed |