Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.33 |
| ▸ | ILK | Q13418 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ATP4A | P20648 | 3/20 | 0.32 |
| ▸ | ATP4B | P51164 | 3/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9386689 | 1.00 | KAT8 (0.45) | KAT8DYRK1ALIPGAHRF2RL3 | |
| SCHEMBL9339030 | 0.74 | KAT8 (0.58) | KAT8DYRK1AHSD17B10ATP4AATP4B | |
| SCHEMBL9387733 | 0.74 | KAT8 (0.58) | KAT8DYRK1AHSD17B10ATP4AATP4B | |
| SCHEMBL9335020 | 0.72 | KAT8 (0.46) | KAT8DYRK1ASNCAHSD17B10AKR1B1 | |
| SCHEMBL9335010 | 0.72 | KAT8 (0.46) | KAT8DYRK1ASNCAHSD17B10AKR1B1 | |
| SCHEMBL9335493 | 0.71 | KAT8 (0.45) | KAT8DYRK1AAHRSNCAHSD17B10 | |
| SCHEMBL9338937 | 0.71 | KAT8 (0.50) | KAT8DYRK1ASNCAHSD17B10 | |
| SCHEMBL9388753 | 0.71 | KAT8 (0.47) | KAT8DYRK1AAHRF2RL3ILK | |
| SCHEMBL9338942 | 0.71 | KAT8 (0.50) | KAT8DYRK1ASNCAHSD17B10 | |
| SCHEMBL9335476 | 0.71 | KAT8 (0.45) | KAT8DYRK1AAHRSNCAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533695-B1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY | PFIZER (US) | 1994-10-05 | — | — | EP | disclosed |
| EP-0533695-A1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY. | PFIZER (US) | 1993-03-31 | — | — | EP | disclosed |
| WO-1991017163-A1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY | PFIZER INC. (US) | 1991-11-14 | — | — | WO | disclosed |