Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29674869 | 1.00 | GAA (0.48) | GAAMAPTCYP3A4TSHRTDP1 | |
| SCHEMBL1612647 | 1.00 | GAA (0.48) | GAAMAPTCYP3A4TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL4380306 | 0.97 | GAA (0.46) | GAAMAPTCYP3A4TSHRTDP1 | |
| SCHEMBL29210 | 0.84 | GAA (0.65) | GAAMAPTCYP3A4TSHRTDP1 | |
| SCHEMBL12819217 | 0.84 | MAPT (0.40) | GAAMAPTCYP3A4TSHRTDP1 | |
| SCHEMBL231997 | 0.78 | CA1 (0.39) | GAAMAPTCA1CA2CA9 | |
| SCHEMBL31441248 | 0.78 | CA1 (0.39) | GAAMAPTCA1CA2CA9 | |
| SCHEMBL1639935 | 0.78 | CA1 (0.54) | GAAMAPTCYP3A4TSHRTDP1 | |
| SCHEMBL4450031 | 0.77 | TDP1 (0.41) | GAAMAPTCYP3A4TSHRTDP1 | |
| SCHEMBL11537346 | 0.77 | MAPT (0.72) | GAAMAPTCYP3A4TSHRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994000124-A1 | GLYCINE RECEPTOR ANTAGONISTS AND THE USE THEREOF | WEBER ECKARD (US) | 1994-01-06 | — | — | WO | disclosed |