Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 10/20 | 0.68 |
| ▸ | DDO | Q99489 | 5/20 | 0.68 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9389414 | 0.90 | DAO (0.58) | DAODDOGRIN1GRIN2A | |
| SCHEMBL16767853 | 0.81 | DAO (1.00) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL8580170 | 0.81 | DAO (0.66) | DAODDO | |
| SCHEMBL9389908 | 0.80 | DAO (0.50) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL9389308 | 0.79 | DAO (0.56) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL9389013 | 0.78 | DAO (0.58) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL9389356 | 0.78 | DAO (0.50) | DAODDOCDK1CDK2 | |
| SCHEMBL9393158 | 0.78 | DAO (0.66) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL9387612 | 0.78 | DAO (0.66) | DAODDO | |
| SCHEMBL9392651 | 0.77 | DAO (0.49) | DAODDOCDK1CDK2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994007500-A1 | 2,5-DIHYDRO-2,5-DIOXO-1H-AZEPINES AND 2,5-DIHYDRO-2-OXO-1H-AZEPINES AND THE USE THEREOF AS EXCITATORY AMINO ACID AND GLYCINE RECEPTOR ANTAGONISTS | WEBER ECKARD (US) | 1994-04-14 | — | — | WO | disclosed |