Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11300892 | 0.91 | MEN1 (0.43) | MEN1KMT2ACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL11345471 | 0.91 | KMT2A (0.43) | MEN1KMT2ACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL9191497 | 0.88 | MEN1 (0.39) | MEN1KMT2ACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL11170960 | 0.87 | HPGD (0.43) | MEN1KMT2ACYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL2763332 | 0.85 | MEN1 (0.37) | MEN1KMT2ACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL3775035 | 0.84 | FOLH1 (0.36) | MEN1KMT2ACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL7591975 | 0.84 | MEN1 (0.38) | MEN1KMT2ACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL3775034 | 0.83 | MEN1 (0.36) | MEN1KMT2ACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL9515039 | 0.83 | MEN1 (0.37) | MEN1KMT2ACYP1A2CYP3A4ALDH1A1 | |
| Valine SCHEMBL11334369 | 0.82 | SLC7A5 (0.36) | MEN1KMT2ACYP1A2CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994005337-A1 | NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT MEDICAL, INC. (US) | 1994-03-17 | — | — | WO | disclosed |
| EP-0308364-B1 | Dicarboxylic acid-bis(3,5-dicarbamoyl-2-4-6-triiodanilides), process for their preparation and X-ray contrast agents containing them | SCHERING AG (DE) | 1993-11-10 | — | — | EP | disclosed |
| WO-1993010825-A1 | NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT MEDICAL, INC. (US) | 1993-06-10 | — | — | WO | disclosed |
| US-5191120-A | Process for preparing nonionic X-ray contrast agents | MALLINCKRODT MEDICAL, INC. (US) | 1993-03-02 | — | — | US | disclosed |
| EP-0504266-A1 | NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT, INC. (US) | 1992-09-23 | — | — | EP | disclosed |
| US-5075502-A | NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT, INC. (US) | 1991-12-24 | — | — | US | disclosed |
| WO-1991009007-A2 | NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT, INC. (US) | 1991-06-27 | — | — | WO | disclosed |
| EP-0308364-A2 | Dicarboxylic acid-bis(3,5-dicarbamoyl-2-4-6-triiodanilides), process for their preparation and X-ray contrast agents containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-03-22 | — | — | EP | disclosed |