Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9391134 | 1.00 | PTAFR (0.44) | PTAFRKCNA3SIGMAR1KDM4EGAA | |
| SCHEMBL9387180 | 0.86 | PTAFR (0.62) | PTAFRKCNA3KDM4EALDH1A1TBXAS1 | |
| SCHEMBL9390517 | 0.86 | PTAFR (0.62) | PTAFRKCNA3KDM4EALDH1A1TBXAS1 | |
| SCHEMBL9387250 | 0.86 | PTAFR (0.62) | PTAFRKCNA3KDM4EALDH1A1TBXAS1 | |
| SCHEMBL9386962 | 0.82 | PTAFR (0.57) | PTAFRKDM4EALDH1A1TSHRTBXAS1 | |
| SCHEMBL9387198 | 0.81 | PTAFR (0.56) | PTAFRSIGMAR1KDM4EGAAALDH1A1 | |
| SCHEMBL9391094 | 0.81 | PTAFR (0.57) | PTAFRKDM4EALDH1A1TBXAS1 | |
| SCHEMBL9386178 | 0.81 | PTAFR (0.57) | PTAFRKDM4EALDH1A1TBXAS1 | |
| SCHEMBL9388172 | 0.79 | PTAFR (0.55) | PTAFRSIGMAR1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9391107 | 0.79 | PTAFR (0.57) | PTAFRSIGMAR1KDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994001434-A1 | BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES AS PAF ANTAGONISTS | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1994-01-20 | — | — | WO | disclosed |