SCHEMBL9392865 — predicted protein targets

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	GRIN2D	O15399	16/20	0.39

▸	GRIN3B	O60391	16/20	0.39

▸	GRIN1	Q05586	16/20	0.39

▸	GRIN2A	Q12879	16/20	0.39

▸	GRIN2B	Q13224	16/20	0.39

▸	GRIN2C	Q14957	16/20	0.39

▸	GRIN3A	Q8TCU5	16/20	0.39

▸	DAO	P14920	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9389375	0.85	GRIN2D (0.51)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL9389445	0.84	GRIN2D (0.46)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL9389410	0.84	GRIN2D (0.38)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL9387869	0.79	GRIN2D (0.46)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL9393393	0.78	GRIN2D (0.45)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL9389012	0.77	GRIN2D (0.40)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL9393192	0.76	GRIN2D (0.43)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL9393306	0.76	GRIN2D (0.54)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL9387878	0.74	GRIN2D (0.49)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL9387752	0.74	GRIN2D (0.38)	GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1994007500-A1	2,5-DIHYDRO-2,5-DIOXO-1H-AZEPINES AND 2,5-DIHYDRO-2-OXO-1H-AZEPINES AND THE USE THEREOF AS EXCITATORY AMINO ACID AND GLYCINE RECEPTOR ANTAGONISTS	WEBER ECKARD (US)	1994-04-14	—	—	WO	disclosed