Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 3/20 | 0.39 |
| ▸ | CASP7 | P55210 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10912832 | 0.81 | KDM4E (0.41) | ALDH1A1KDM4EGAAHSD17B10CASP1 | |
| SCHEMBL22702928 | 0.78 | KDM4E (0.39) | ALDH1A1KDM4EGAAHSD17B10CASP1 | |
| SCHEMBL10911434 | 0.78 | HTR1D (0.39) | ALDH1A1KDM4EGAAHSD17B10CASP1 | |
| SCHEMBL10909711 | 0.78 | KDM4E (0.42) | ALDH1A1KDM4EGAAHSD17B10CASP1 | |
| SCHEMBL9396807 | 0.77 | PARP1 (0.40) | PARP1SRC | |
| SCHEMBL9181279 | 0.75 | GAA (0.39) | ALDH1A1KDM4EGAAHSD17B10CASP1 | |
| SCHEMBL4947965 | 0.74 | KDM4E (0.33) | ALDH1A1KDM4EGAAHSD17B10CASP1 | |
| SCHEMBL9175444 | 0.73 | KDM4E (0.43) | ALDH1A1KDM4EGAAHSD17B10CASP1 | |
| SCHEMBL16383855 | 0.73 | MAPT (0.43) | ALDH1A1KDM4EGAAHSD17B10CASP1 | |
| Hydrochloric Acid SCHEMBL30829603 | 0.71 | KDM4E (0.53) | ALDH1A1KDM4EGAAHSD17B10CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994028863-A1 | 8-AMINO-1,2,3,4-TETRAHYDROQUINOLINES AS COUPLERS IN DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1994-12-22 | — | — | WO | claimed |
| WO-1994028863-A1 | 8-AMINO-1,2,3,4-TETRAHYDROQUINOLINES AS COUPLERS IN DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1994-12-22 | — | — | WO | disclosed |