Nitrogen

Nitrogen

SCHEMBL9395652

Clc1cccc(Cl)c1Cl.N#N

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.55
CYP1A2 P05177 3/20 0.50
PNMT P11086 2/20 0.50
LMNA P02545 2/20 0.50
CYP2A6 P11509 2/20 0.50
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
NFKB1 P19838 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
ALDH1A1 P00352 4/20 0.42
IDO1 P14902 2/20 0.42
GLA P06280 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3991309 0.93 TSHR (0.61) TSHRCYP1A2PNMTLMNACYP2A6
SCHEMBL23239 0.93
Cyanide SCHEMBL28124146 0.90 TSHR (0.52) TSHRCYP1A2PNMTLMNACYP2A6
Hydrochloric Acid SCHEMBL31618288 0.89 TSHR (0.58) TSHRCYP1A2PNMTLMNACYP2A6
Phosphine SCHEMBL22230521 0.89 TSHR (0.58) TSHRCYP1A2PNMTLMNACYP2A6
Ammonia Solution, Strong SCHEMBL27433518 0.89 TSHR (0.58) TSHRCYP1A2PNMTLMNACYP2A6
SCHEMBL1395277 0.89 TSHR (0.58) TSHRCYP1A2PNMTLMNACYP2A6
Fluoride SCHEMBL28376896 0.89 TSHR (0.58) TSHRCYP1A2PNMTLMNACYP2A6
SCHEMBL10786340 0.89 TSHR (0.58) TSHRCYP1A2PNMTLMNACYP2A6
Water SCHEMBL27915574 0.89 TSHR (0.58) TSHRCYP1A2PNMTLMNACYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0319452-B1 Monoazo pigments, process to manufacture them and their use HOECHST AG (DE) 1994-05-18 EP claimed
JP-2000662-A None JP disclosed
JP-H02662-A MONOAZO PIGMENT, ITS MANUFACTURE, AND ITS APPLICATION HOECHST AG 1990-01-05 JP disclosed