Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 12/20 | 0.68 |
| ▸ | SRD5A1 | P18405 | 6/20 | 0.68 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9391101 | 0.92 | SRD5A2 (0.68) | SRD5A2SRD5A1ESR1ARESR2 | |
| SCHEMBL9391082 | 0.91 | SRD5A2 (0.82) | SRD5A2SRD5A1 | |
| SCHEMBL8151553 | 0.90 | SRD5A2 (0.83) | SRD5A2SRD5A1 | |
| SCHEMBL8151554 | 0.90 | SRD5A2 (0.83) | SRD5A2SRD5A1 | |
| SCHEMBL8994170 | 0.87 | SRD5A2 (0.69) | SRD5A2SRD5A1ESR1ARESR2 | |
| SCHEMBL9396243 | 0.86 | SRD5A2 (0.68) | SRD5A2SRD5A1ESR1ARESR2 | |
| SCHEMBL9113743 | 0.86 | SRD5A2 (0.68) | SRD5A2SRD5A1ESR1ARESR2 | |
| SCHEMBL9111539 | 0.86 | SRD5A2 (0.67) | SRD5A2SRD5A1ESR1ARESR2 | |
| SCHEMBL9110502 | 0.84 | SRD5A2 (0.65) | SRD5A2SRD5A1ESR1ARESR2 | |
| SCHEMBL9392669 | 0.84 | SRD5A2 (0.66) | SRD5A2SRD5A1ESR1ARESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994022897-A1 | 17β-SUBSTITUTED ANDROSTA-3,5-DIENE DERIVATIVES | CIBA-GEIGY AG (CH) | 1994-10-13 | — | — | WO | disclosed |