SCHEMBL9396282

SCHEMBL9396282

O=C1c2cccc(OCc3ccccc3)c2C(=O)N1c1ccc(F)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
GRM5 P41594 4/20 0.53
L3MBTL1 Q9Y468 3/20 0.51
LMNA P02545 3/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
NCOA3 Q9Y6Q9 1/20 0.51
PGR P06401 1/20 0.47
HSPA1A P0DMV8 1/20 0.47
PABPC1 P11940 1/20 0.47
DDB1 Q16531 1/20 0.46
CRBN Q96SW2 1/20 0.46
IKZF3 Q9UKT9 1/20 0.46
POLB P06746 2/20 0.46
RECQL P46063 1/20 0.46
HTT P42858 3/20 0.46
ALDH1A1 P00352 1/20 0.46
KDM4E B2RXH2 1/20 0.44
HPGD P15428 1/20 0.44
NR1H3 Q13133 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9396286 0.91 GRM5 (0.55) MEN1KMT2AGRM5L3MBTL1LMNA
SCHEMBL5388051 0.77 HPGD (0.61) MEN1KMT2ALMNASMN1; SMN2PGR
SCHEMBL448847 0.73 KMT2A (0.64) MEN1KMT2AGRM5PGRPOLB
SCHEMBL8216313 0.73 MAPT (0.69) L3MBTL1TDP1
SCHEMBL16072720 0.73 KCNA3 (0.58) L3MBTL1HTTTDP1
SCHEMBL13265370 0.72 ADORA2A (0.61) MEN1KMT2APGRHSPA1APABPC1
SCHEMBL11696190 0.71 HPGD (0.67) MEN1KMT2ALMNASMN1; SMN2PGR
SCHEMBL9173435 0.71 KCNA3 (0.56) L3MBTL1HTTTDP1
SCHEMBL25773788 0.71 HTT (0.48) MEN1KMT2AGRM5L3MBTL1LMNA
SCHEMBL11352025 0.71 HPGD (0.67) MEN1KMT2AGRM5LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1994026696-A1 HERBICIDAL CYCLOHEXANES DUNLENA PTY. LIMITED (AU) 1994-11-24 WO disclosed
WO-1993010081-A1 HERBICIDAL 2(SUBSTITUTED OXIME)-CYCLOHEXAN-1,3-DIONE DERIVATIVES DUNLENA PTY. LIMITED (AU) 1993-05-27 WO disclosed