Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 14/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 13/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.40 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9396756 | 1.00 | HDAC6 (0.44) | HDAC6HSP90AB1HSP90AA1HDAC1HDAC4 | |
| SCHEMBL8446252 | 0.87 | HDAC6 (0.42) | HDAC6HSP90AB1HSP90AA1HDAC1HDAC4 | |
| SCHEMBL9225003 | 0.86 | HDAC6 (0.41) | HDAC6HSP90AB1HSP90AA1HDAC1HDAC4 | |
| SCHEMBL9222934 | 0.84 | HDAC6 (0.39) | HDAC6HSP90AB1HSP90AA1HDAC1HDAC4 | |
| SCHEMBL9255723 | 0.84 | BCHE (0.32) | — | |
| SCHEMBL9255726 | 0.84 | BCHE (0.32) | — | |
| SCHEMBL9257397 | 0.84 | HDAC1 (0.43) | HDAC6HSP90AB1HSP90AA1HDAC1HDAC4 | |
| SCHEMBL9411742 | 0.82 | BLM (0.48) | — | |
| SCHEMBL8449238 | 0.78 | HDAC6 (0.44) | HDAC6HSP90AB1HSP90AA1HDAC1HDAC4 | |
| SCHEMBL7452547 | 0.78 | HDAC6 (0.44) | HDAC6HSP90AB1HSP90AA1HDAC1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342840-A | Viricides | AJINOMOTO CO., INC. (JP) | 1994-08-30 | — | — | US | disclosed |