Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL15391982 | 0.92 | CA1 (0.61) | — | |
| Acetic Acid SCHEMBL10634195 | 0.92 | CA1 (0.61) | — | |
| Acetic Acid SCHEMBL7960655 | 0.85 | — | — | |
| Acetic Acid SCHEMBL548946 | 0.85 | — | — | |
| Acetic Acid SCHEMBL93969 | 0.85 | — | — | |
| Acetic Acid SCHEMBL2289 | 0.83 | — | — | |
| Acetic Acid SCHEMBL1331799 | 0.83 | — | — | |
| Acetic Acid SCHEMBL1332333 | 0.83 | — | — | |
| Acetic Acid SCHEMBL1332530 | 0.83 | — | — | |
| Acetic Acid SCHEMBL153505 | 0.83 | CA1 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2425837-B1 | USE OF CELL AUTOPHAGY (TYPE II CELL APOPTOSIS) INHIBITORS | INST BASIC MED SCIENCES PLA (CN) | 2015-03-04 | — | — | EP | disclosed |
| US-20120238566-A1 | USE OF CELL AUTOPHAGY (TYPE II CELL APOPTOSIS) INHIBITORS | INSTITUTE OF BASIC MEDICAL SCIENCES CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2012-09-20 | — | — | US | disclosed |
| EP-2425837-A1 | USE OF CELL AUTOPHAGY (TYPE II CELL APOPTOSIS) INHIBITORS | Institute of Basic Medical Sciences Chinese Academy of Medical Sciences (CN) | 2012-03-07 | — | — | EP | disclosed |