Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 9/20 | 0.43 |
| ▸ | PYGM | P11217 | 8/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | PPOX | P50336 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28980887 | 0.81 | POLB (0.55) | POLBKDM4EALDH1A1PYGLPYGM | |
| SCHEMBL29441323 | 0.81 | POLB (0.55) | POLBKDM4EALDH1A1PYGLPYGM | |
| SCHEMBL260857 | 0.81 | POLB (0.58) | POLBKDM4EALDH1A1PYGLPYGM | |
| SCHEMBL29401261 | 0.81 | POLB (0.58) | POLBKDM4EALDH1A1PYGLPYGM | |
| SCHEMBL21437005 | 0.80 | POLB (0.56) | POLBKDM4EALDH1A1PYGLPYGM | |
| Water SCHEMBL3777569 | 0.80 | POLB (0.56) | POLBKDM4EALDH1A1PYGLPYGM | |
| SCHEMBL21437004 | 0.80 | POLB (0.56) | POLBKDM4EALDH1A1PYGLPYGM | |
| SCHEMBL8628820 | 0.79 | TDP1 (0.49) | POLBKDM4EALDH1A1PYGLPYGM | |
| SCHEMBL8906676 | 0.78 | POLB (0.55) | POLBKDM4EALDH1A1PYGLPYGM | |
| SCHEMBL29907832 | 0.77 | POLB (0.54) | POLBKDM4EALDH1A1PYGLPYGM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5357033-A | Forming polyetherimmides having non-symmetrical polar radicals | GENERAL ELECTRIC COMPANY (US) | 1994-10-18 | — | — | US | disclosed |