Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 12/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9188492 | 1.00 | DAO (0.40) | DAOTRPV4KDM1AKCNJ1KCNH2 | |
| SCHEMBL9188498 | 1.00 | DAO (0.40) | DAOTRPV4KDM1AKCNJ1KCNH2 | |
| SCHEMBL9190022 | 0.95 | DAO (0.40) | DAOTRPV4KDM1AKCNJ1KCNH2 | |
| SCHEMBL9398421 | 0.95 | DAO (0.40) | DAOTRPV4KDM1AKCNJ1KCNH2 | |
| SCHEMBL9190019 | 0.95 | DAO (0.40) | DAOTRPV4KDM1AKCNJ1KCNH2 | |
| SCHEMBL8377162 | 0.91 | DAO (0.43) | DAOTRPV4KDM1AKCNJ1KCNH2 | |
| SCHEMBL8377734 | 0.91 | DAO (0.43) | DAOTRPV4KDM1AKCNJ1KCNH2 | |
| SCHEMBL8377728 | 0.91 | DAO (0.43) | DAOTRPV4KDM1AKCNJ1KCNH2 | |
| SCHEMBL10345350 | 0.91 | DAO (0.40) | DAOTRPV4KDM1AKCNJ1KCNH2 | |
| SCHEMBL9620711 | 0.91 | DAO (0.40) | DAOTRPV4KDM1AKCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5346647-A | Cyclohexane compounds used in liquid crystalline mixtures | HOFFMANN-LA ROCHE INC. (US) | 1994-09-13 | — | — | US | disclosed |