Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 9/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9398632 | 0.92 | OPRL1 (0.39) | OPRL1CYP2C9MAPTSLC6A2SLC6A4 | |
| SCHEMBL9399536 | 0.92 | OPRL1 (0.39) | OPRL1CYP2C9MAPTSLC6A2SLC6A4 | |
| SCHEMBL9399778 | 0.89 | OPRL1 (0.41) | OPRL1CYP2C9MAPTSLC6A2SLC6A4 | |
| SCHEMBL10606725 | 0.85 | OPRL1 (0.42) | OPRL1CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL9399395 | 0.84 | SPHK1 (0.43) | OPRL1CYP2C9SLC6A2SLC6A4SKP2 | |
| SCHEMBL9398885 | 0.83 | SPHK1 (0.45) | OPRL1CYP2C9SLC6A2SLC6A4SKP2 | |
| SCHEMBL9399816 | 0.83 | SPHK1 (0.45) | OPRL1CYP2C9SLC6A2SLC6A4SKP2 | |
| SCHEMBL9398560 | 0.83 | SPHK1 (0.45) | OPRL1CYP2C9SLC6A2SLC6A4SKP2 | |
| SCHEMBL9398855 | 0.83 | OPRL1 (0.47) | OPRL1CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL12739700 | 0.83 | SLC6A2 (0.40) | OPRL1CYP2C9SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338483-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1994-08-16 | — | — | US | disclosed |
| US-5310501-A | Anisotropic compounds having Nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1994-05-10 | — | — | US | disclosed |
| US-5227484-A | ANISOTROPIC COMPOUNDS HAVING NEMATIC PHASE AND LIQUID CRYSTAL MIXTURES | MERCK PATENT GMBH (DE) | 1993-07-13 | — | — | US | disclosed |
| US-5179101-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1993-01-12 | — | — | US | disclosed |
| US-5047170-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1991-09-10 | — | — | US | disclosed |
| US-4808333-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1989-02-28 | — | — | US | disclosed |
| EP-0084194-B1 | LIQUID CRYSTAL MIXTURES | MERCK PATENT GmbH (DE) | 1986-04-30 | — | — | EP | disclosed |
| EP-0084194-A1 | Liquid crystal mixtures | MERCK PATENT GmbH (DE) | 1983-07-27 | — | — | EP | disclosed |