Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10980962 | 1.00 | SMN1; SMN2 (0.59) | SMN1; SMN2GLAS1PR1CSNK2A1BACE1 | |
| SCHEMBL10986578 | 0.99 | SMN1; SMN2 (0.58) | SMN1; SMN2GLAS1PR1CSNK2A1BACE1 | |
| SCHEMBL10984442 | 0.99 | SMN1; SMN2 (0.58) | SMN1; SMN2GLAS1PR1CSNK2A1BACE1 | |
| SCHEMBL10976576 | 0.99 | SMN1; SMN2 (0.58) | SMN1; SMN2GLAS1PR1CSNK2A1BACE1 | |
| SCHEMBL10975791 | 0.97 | SMN1; SMN2 (0.56) | SMN1; SMN2GLAS1PR1CSNK2A1BACE1 | |
| SCHEMBL10982899 | 0.96 | SMN1; SMN2 (0.55) | SMN1; SMN2GLAS1PR1CSNK2A1BACE1 | |
| SCHEMBL10979500 | 0.96 | SMN1; SMN2 (0.55) | SMN1; SMN2GLAS1PR1CSNK2A1BACE1 | |
| SCHEMBL10981424 | 0.96 | SMN1; SMN2 (0.55) | SMN1; SMN2GLAS1PR1CSNK2A1BACE1 | |
| SCHEMBL10975599 | 0.96 | SMN1; SMN2 (0.55) | SMN1; SMN2GLAS1PR1CSNK2A1BACE1 | |
| SCHEMBL10975775 | 0.96 | SMN1; SMN2 (0.55) | SMN1; SMN2GLAS1PR1CSNK2A1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338483-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1994-08-16 | — | — | US | disclosed |
| US-5310501-A | Anisotropic compounds having Nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1994-05-10 | — | — | US | disclosed |
| US-5227484-A | ANISOTROPIC COMPOUNDS HAVING NEMATIC PHASE AND LIQUID CRYSTAL MIXTURES | MERCK PATENT GMBH (DE) | 1993-07-13 | — | — | US | disclosed |
| US-5179101-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1993-01-12 | — | — | US | disclosed |
| US-5047170-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1991-09-10 | — | — | US | disclosed |
| US-4808333-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1989-02-28 | — | — | US | disclosed |