Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9398975 | 0.98 | GLA (0.55) | SMN1; SMN2GLAS1PR1S1PR2S1PR3 | |
| SCHEMBL9398910 | 0.93 | S1PR1 (0.56) | SMN1; SMN2GLAS1PR1S1PR2S1PR3 | |
| SCHEMBL9399009 | 0.92 | SMN1; SMN2 (0.50) | SMN1; SMN2GLAS1PR1S1PR2S1PR3 | |
| SCHEMBL6468437 | 0.89 | S1PR1 (0.49) | SMN1; SMN2GLAS1PR1S1PR2S1PR3 | |
| SCHEMBL12522468 | 0.86 | S1PR1 (0.50) | SMN1; SMN2GLAS1PR1S1PR2S1PR3 | |
| SCHEMBL12522476 | 0.86 | GLA (0.50) | SMN1; SMN2GLAS1PR1S1PR2S1PR3 | |
| SCHEMBL9399031 | 0.86 | S1PR1 (0.46) | SMN1; SMN2GLAS1PR1S1PR2S1PR3 | |
| SCHEMBL12447022 | 0.86 | CSNK2A1 (0.46) | SMN1; SMN2GLAS1PR1S1PR2S1PR3 | |
| SCHEMBL9399771 | 0.85 | S1PR2 (0.45) | SMN1; SMN2GLAS1PR1S1PR2S1PR3 | |
| SCHEMBL19608555 | 0.84 | S1PR1 (0.54) | SMN1; SMN2GLAS1PR1S1PR2S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338483-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1994-08-16 | — | — | US | disclosed |
| US-5310501-A | Anisotropic compounds having Nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1994-05-10 | — | — | US | disclosed |
| US-5227484-A | ANISOTROPIC COMPOUNDS HAVING NEMATIC PHASE AND LIQUID CRYSTAL MIXTURES | MERCK PATENT GMBH (DE) | 1993-07-13 | — | — | US | disclosed |
| US-5179101-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1993-01-12 | — | — | US | disclosed |
| US-5047170-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1991-09-10 | — | — | US | disclosed |
| US-4808333-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1989-02-28 | — | — | US | disclosed |
| EP-0084194-B1 | LIQUID CRYSTAL MIXTURES | MERCK PATENT GmbH (DE) | 1986-04-30 | — | — | EP | disclosed |
| EP-0084194-A1 | Liquid crystal mixtures | MERCK PATENT GmbH (DE) | 1983-07-27 | — | — | EP | disclosed |