Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 9/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9399340 | 0.89 | HPGD (0.33) | ABL1TP53 | |
| SCHEMBL9399137 | 0.89 | GRM2 (0.35) | TP53S1PR1 | |
| SCHEMBL9399829 | 0.88 | TLR9 (0.39) | GRIN1GRIN2BTDP1FFAR4S1PR1 | |
| SCHEMBL9398713 | 0.87 | S1PR1 (0.41) | S1PR1 | |
| SCHEMBL9398801 | 0.86 | ACACB (0.35) | TDP1FFAR4CYP11B1CYP11B2S1PR1 | |
| SCHEMBL9399272 | 0.86 | HDAC4 (0.37) | GRIN1GRIN2BTDP1FFAR4CYP11B1 | |
| SCHEMBL9399283 | 0.86 | HDAC4 (0.37) | GRIN1GRIN2BTDP1FFAR4CYP11B1 | |
| SCHEMBL9399470 | 0.86 | GRIN2B (0.36) | GRIN1GRIN2BTDP1FFAR4CYP11B1 | |
| SCHEMBL9399480 | 0.86 | GRIN2B (0.36) | GRIN1GRIN2BTDP1FFAR4CYP11B1 | |
| SCHEMBL9399711 | 0.85 | FFAR4 (0.39) | GRIN1GRIN2BTDP1FFAR4FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338483-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1994-08-16 | — | — | US | disclosed |
| US-5310501-A | Anisotropic compounds having Nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1994-05-10 | — | — | US | disclosed |
| US-5227484-A | ANISOTROPIC COMPOUNDS HAVING NEMATIC PHASE AND LIQUID CRYSTAL MIXTURES | MERCK PATENT GMBH (DE) | 1993-07-13 | — | — | US | disclosed |
| US-5047170-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1991-09-10 | — | — | US | disclosed |
| US-4808333-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1989-02-28 | — | — | US | disclosed |
| EP-0084194-A1 | Liquid crystal mixtures | MERCK PATENT GmbH (DE) | 1983-07-27 | — | — | EP | disclosed |