Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9591848 | 0.90 | GAA (0.35) | TSHRALDH1A1ESR1HSD17B10KMT2A | |
| SCHEMBL11468979 | 0.89 | GAA (0.36) | TSHRALDH1A1KMT2AMEN1GAA | |
| SCHEMBL7686107 | 0.89 | GAA (0.34) | TSHRALDH1A1ESR1HSD17B10KMT2A | |
| SCHEMBL7509051 | 0.88 | GAA (0.36) | TSHRALDH1A1KMT2AMEN1GAA | |
| SCHEMBL31364 | 0.88 | GAA (0.36) | TSHRALDH1A1KMT2AMEN1GAA | |
| SCHEMBL12933651 | 0.87 | GAA (0.36) | TSHRALDH1A1KMT2AMEN1GAA | |
| SCHEMBL12897914 | 0.87 | GAA (0.35) | TSHRALDH1A1KMT2AMEN1GAA | |
| SCHEMBL9589852 | 0.86 | GAA (0.35) | TSHRALDH1A1KMT2AMEN1GAA | |
| SCHEMBL11487382 | 0.86 | GAA (0.35) | TSHRALDH1A1KMT2AMEN1GAA | |
| SCHEMBL11213179 | 0.85 | GAA (0.35) | TSHRALDH1A1KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300647-A | Light stabilizers for polyolefins, other polymers | CIBA-GEIGY CORPORATION (US) | 1994-04-05 | — | — | US | claimed |
| US-5300647-A | Light stabilizers for polyolefins, other polymers | CIBA-GEIGY CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |
| EP-0309400-B1 | N-acyloxy hindered amine stabilizers | CIBA GEIGY AG (CH) | 1994-03-02 | — | — | EP | disclosed |
| US-4691015-A | STABILIZERS | CIBA-GEIGY CORPORATION (US) | 1987-09-01 | — | — | US | disclosed |