Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.73 |
| ▸ | TP53 | P04637 | 4/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | HTR2B | P41595 | 1/20 | 0.73 |
| ▸ | RECQL | P46063 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | HTR2C | P28335 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 8/20 | 0.52 |
| ▸ | RAB9A | P51151 | 8/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9400518 | 0.97 | MEN1 (0.69) | MEN1KMT2AMAPTTP53KDM4E | |
| SCHEMBL17330341 | 0.86 | MEN1 (0.69) | MEN1KMT2AMAPTTP53KDM4E | |
| SCHEMBL29391435 | 0.85 | MAPT (1.00) | MEN1KMT2AMAPTTP53KDM4E | |
| SCHEMBL29729330 | 0.85 | MAPT (1.00) | MEN1KMT2AMAPTTP53KDM4E | |
| SCHEMBL173735 | 0.85 | MAPT (1.00) | MEN1KMT2AMAPTTP53KDM4E | |
| Hydrochloric Acid SCHEMBL2116886 | 0.84 | HTR2C (1.00) | MEN1KMT2AMAPTTP53KDM4E | |
| Hydrochloric Acid SCHEMBL31077673 | 0.84 | HTR2C (1.00) | MEN1KMT2AMAPTTP53KDM4E | |
| SCHEMBL9400523 | 0.79 | MAPT (0.47) | MEN1KMT2AMAPTTP53KDM4E | |
| SCHEMBL9400617 | 0.78 | MEN1 (0.82) | MEN1KMT2AMAPTTP53KDM4E | |
| Hydrochloric Acid SCHEMBL9400545 | 0.77 | HTR2C (0.82) | MEN1KMT2AMAPTTP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328922-A | Anxiolytic and antidepressant activity | BEECHAM GROUP P.L.C. (GB) | 1994-07-12 | — | — | US | claimed |
| WO-1993018026-A1 | INDOLE UREAS AS 5-HT1C RECEPTOR ANTOGONISTS | BEECHAM GROUP PLC (GB) | 1993-09-16 | — | — | WO | claimed |
| WO-1993016694-A1 | USE OF INDYLPYRIDYLUREAS TO HEAL THE EFFECTS OF BRAIN OR SPIRAL TRAUMA | SMITHKLINE BEECHAM PLC (GB) | 1993-09-02 | — | — | WO | claimed |
| EP-0550507-A1 | INDOLE UREAS AS 5 HT RECEPTOR ANTAGONIST | Beecham Group p.l.c. (GB) | 1993-07-14 | — | — | EP | claimed |
| WO-1992005170-A1 | INDOLE UREAS AS 5 HT RECEPTOR ANTAGONIST | BEECHAM GROUP PLC (GB) | 1992-04-02 | — | — | WO | claimed |
| WO-1993016694-A1 | USE OF INDYLPYRIDYLUREAS TO HEAL THE EFFECTS OF BRAIN OR SPIRAL TRAUMA | SMITHKLINE BEECHAM PLC (GB) | 1993-09-02 | — | — | WO | disclosed |