Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 14/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401771 | 0.89 | CACNA1B (0.48) | MEN1KMT2ACACNA1BADORA3HTT | |
| SCHEMBL9401870 | 0.89 | MAPT (0.49) | MEN1ALDH1A1KMT2AMAPTCACNA1B | |
| SCHEMBL9401785 | 0.88 | CACNA1B (0.44) | MEN1KMT2ACACNA1BADORA3HTT | |
| SCHEMBL9401715 | 0.88 | CACNA1B (0.61) | MEN1KMT2ACACNA1BADORA3HTT | |
| SCHEMBL9401528 | 0.86 | CACNA1B (0.60) | MEN1KMT2ACACNA1BADORA3HTT | |
| SCHEMBL9401649 | 0.85 | CACNA1B (0.46) | MEN1KMT2ACACNA1BADORA3HTT | |
| SCHEMBL9401620 | 0.85 | CACNA1B (0.46) | MEN1ALDH1A1KMT2AMAPTCACNA1B | |
| SCHEMBL7293440 | 0.85 | CACNA1B (0.64) | MEN1KMT2ACACNA1BADORA3HTT | |
| SCHEMBL9401598 | 0.85 | CACNA1B (0.47) | MEN1ALDH1A1KMT2AMAPTCACNA1B | |
| SCHEMBL9401615 | 0.85 | CACNA1B (0.61) | MEN1KMT2ACACNA1BADORA3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286869-A | Vasodilators and anticoagulants | FUJIREBIO KABUSHIKI KAISHA (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0403957-A2 | Optical active 1,4-dihydropyridine derivates | FUJIREBIO INC. (JP) | 1990-12-27 | — | — | EP | disclosed |