Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26598830 | 0.93 | — | — | |
| SCHEMBL25619096 | 0.71 | — | — | |
| SCHEMBL25619149 | 0.71 | — | — | |
| SCHEMBL18585851 | 0.70 | CA1 (0.36) | CA1CA9 | |
| SCHEMBL9444648 | 0.68 | — | — | |
| SCHEMBL11486086 | 0.67 | TSHR (0.36) | HTTLMNATSHR | |
| SCHEMBL9444644 | 0.67 | POLB (0.37) | HTTLMNATSHR | |
| SCHEMBL22387246 | 0.67 | TRIM24 (0.48) | CA1CA9 | |
| SCHEMBL15540440 | 0.67 | — | — | |
| SCHEMBL2775678 | 0.66 | TRIM24 (0.37) | LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105755846-B | A kind of water suction Breathable artificial leather and preparation method thereof | 江苏盈泰新材料科技有限公司 | 2018-11-13 | — | — | CN | claimed |
| CN-107827721-A | A kind of method for synthesizing 4 fluorine cyclohexanone | 上海恩氟佳科技有限公司 | 2018-03-23 | — | — | CN | claimed |
| CN-101475456-B | Method for preparing cyclohexyl formaldehyde by ion liquid catalysis | HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2011-12-28 | — | — | CN | claimed |
| US-7868029-B2 | Process for the preparation of 2-amino-4,5,6,7-tetrahydro-6-aminobenzothiazoles from cyclohexanes and cyclohexanones as intermediates | GENERICS [UK] LIMITED (GB) | 2011-01-11 | — | — | US | claimed |
| EP-1542981-B1 | PROCESS FOR THE PREPARATION OF 2-AMINO-4,5,6,7-TETRAHYDRO-6-AMINOBENZOTHIAZOLES FROM CYCLOHEXANES AND CYCLOHEXANONES AS INTERMEDIATES | GENERICS UK LTD (GB) | 2009-07-22 | — | — | EP | claimed |
| CN-101475456-A | Method for preparing cyclohexyl formaldehyde by ion liquid catalysis | UNIV HEBEI SCIENCE & TECH (CN) | 2009-07-08 | — | — | CN | claimed |
| US-20240059672-A1 | METHOD OF PREPARING PRALSETINIB | BLUEPRINT MEDICINES CORPORATION | 2024-02-22 | — | — | US | disclosed |
| EP-4255892-A1 | METHOD OF PREPARING PRALSETINIB | Blueprint Medicines Corporation (US) | 2023-10-11 | — | — | EP | disclosed |
| CN-116724024-A | Process for preparing platinib | 缆图药品公司 | 2023-09-08 | — | — | CN | disclosed |
| EP-4019491-A1 | PROCESS FOR PREPARING A SYNTHETIC INTERMEDIATE USEFUL IN THE PREPARATION OF AN APOPTOSIS-INDUCING AGENT | AbbVie Ireland Unlimited Company (IE) | 2022-06-29 | — | — | EP | disclosed |
| WO-2022120136-A1 | METHOD OF PREPARING PRALSETINIB | BLUEPRINT MEDICINES CORPORATION (US) | 2022-06-09 | — | — | WO | disclosed |
| EP-3954687-A1 | PROCESSES AND INTERMEDIATES USEFUL IN THE PREPARATION OF AN APOPTOSIS-INDUCING AGENT | AbbVie Ireland Unlimited Company (IE) | 2022-02-16 | — | — | EP | disclosed |
| EP-3569588-A1 | PROCESS FOR PREPARING A SYNTHETIC INTERMEDIATE USEFUL IN THE PREPARATION OF AN APOPTOSIS-INDUCING AGENT | AbbVie Inc. (US) | 2019-11-20 | — | — | EP | disclosed |
| WO-1995031441-A1 | HETEROCYCLYLAMINO- AND HETEROCYCLYLOXY-CYCLOALKYL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-11-23 | — | — | WO | disclosed |
| WO-1995014469-A1 | NOVEL SPIROCYCLES | MERCK & CO., INC. (US) | 1995-06-01 | — | — | WO | disclosed |
| US-5403846-A | Antiarrhythmic agents | MERCK & CO., INC. (US) | 1995-04-04 | — | — | US | disclosed |
| US-5370822-A | Liquid crystals | CHISSO CORPORATION (JP) | 1994-12-06 | — | — | US | disclosed |
| EP-0588291-A1 | 2-Fluorobenzonitrile derivative | Chisso Corporation (JP) | 1994-03-23 | — | — | EP | disclosed |
| EP-0257048-A1 | OPTICALLY ACTIVE COMPOUNDS. | MERCK PATENT GMBH (DE) | 1988-03-02 | — | — | EP | disclosed |
| WO-1987005018-A2 | OPTICALLY ACTIVE COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1987-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240059672-A1 | METHOD OF PREPARING PRALSETINIB | PCSK9, NRAS, LPXN | HTT 3429/4885CA1 4633/4885CA9 1110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.