Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 16/20 | 0.72 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MLNR | O43193 | 1/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.62 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.62 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.62 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.62 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.53 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.53 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.53 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290012 | 1.00 | CACNA1B (0.72) | CACNA1BCACNA1CADORA3MEN1KMT2A | |
| SCHEMBL9401816 | 1.00 | CACNA1B (0.72) | CACNA1BCACNA1CADORA3MEN1KMT2A | |
| SCHEMBL7290001 | 1.00 | CACNA1B (0.72) | CACNA1BCACNA1CADORA3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9401849 | 0.99 | CACNA1B (0.71) | CACNA1BCACNA1CADORA3MEN1KMT2A | |
| SCHEMBL7291859 | 0.97 | CACNA1B (0.66) | CACNA1BCACNA1CADORA3MEN1KMT2A | |
| SCHEMBL9401719 | 0.97 | CACNA1B (0.66) | CACNA1BCACNA1CADORA3MEN1KMT2A | |
| SCHEMBL9401942 | 0.96 | CACNA1B (0.70) | CACNA1BCACNA1CADORA3MEN1KMT2A | |
| SCHEMBL9401944 | 0.96 | CACNA1B (0.70) | CACNA1BCACNA1CADORA3MEN1KMT2A | |
| SCHEMBL9401953 | 0.96 | CACNA1B (0.70) | CACNA1BCACNA1CADORA3MEN1KMT2A | |
| SCHEMBL9401968 | 0.95 | CACNA1B (0.64) | CACNA1BCACNA1CADORA3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286869-A | Vasodilators and anticoagulants | FUJIREBIO KABUSHIKI KAISHA (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0403957-A2 | Optical active 1,4-dihydropyridine derivates | FUJIREBIO INC. (JP) | 1990-12-27 | — | — | EP | disclosed |