Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 11/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401514 | 1.00 | MEN1 (0.51) | MEN1KMT2AALDH1A1MAPTCACNA1B | |
| SCHEMBL9401863 | 0.89 | CYP1A2 (0.48) | MEN1KMT2AMAPTCACNA1BCYP1A2 | |
| SCHEMBL9401858 | 0.89 | CYP1A2 (0.48) | MEN1KMT2AMAPTCACNA1BCYP1A2 | |
| SCHEMBL9401768 | 0.89 | CACNA1B (0.47) | MEN1KMT2ACACNA1BCYP1A2TBXAS1 | |
| SCHEMBL9401779 | 0.88 | CACNA1B (0.46) | MEN1KMT2ACACNA1BCYP1A2TBXAS1 | |
| SCHEMBL9401706 | 0.88 | CACNA1B (0.59) | MEN1KMT2ACACNA1BADORA3TBXAS1 | |
| SCHEMBL9401702 | 0.88 | CACNA1B (0.59) | MEN1KMT2ACACNA1BADORA3TBXAS1 | |
| SCHEMBL9401508 | 0.87 | CACNA1B (0.59) | MEN1KMT2ACACNA1BCYP1A2TBXAS1 | |
| SCHEMBL9401515 | 0.87 | CACNA1B (0.59) | MEN1KMT2ACACNA1BCYP1A2TBXAS1 | |
| SCHEMBL7293425 | 0.86 | CACNA1B (0.63) | MEN1KMT2ACACNA1BADORA3TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286869-A | Vasodilators and anticoagulants | FUJIREBIO KABUSHIKI KAISHA (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0403957-A2 | Optical active 1,4-dihydropyridine derivates | FUJIREBIO INC. (JP) | 1990-12-27 | — | — | EP | disclosed |