Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 3/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9663400 | 0.91 | MCHR1 (0.38) | LMNAKDM4EALDH1A1MAPTGAA | |
| SCHEMBL9401850 | 0.91 | MCHR1 (0.38) | LMNAKDM4EALDH1A1MAPTGAA | |
| SCHEMBL9401823 | 0.87 | KDM4E (0.42) | LMNAKDM4EALDH1A1MAPTGAA | |
| SCHEMBL9401611 | 0.84 | SLC6A4 (0.39) | LMNACYP3A4NR1I2CYP1A2CYP2D6 | |
| SCHEMBL9318482 | 0.84 | CYP3A4 (0.49) | LMNAKDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL11982878 | 0.84 | CYP3A4 (0.49) | LMNAKDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL11982876 | 0.84 | CYP3A4 (0.49) | LMNAKDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL9401622 | 0.80 | CYP3A4 (0.37) | LMNAKDM4EALDH1A1MAPTGAA | |
| SCHEMBL9664041 | 0.80 | NR1I2 (0.37) | LMNAKDM4EALDH1A1MAPTCYP3A4 | |
| SCHEMBL9318996 | 0.79 | KDM4E (0.47) | LMNAKDM4EALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332748-A | Antiischemic, antianoxic | ROUSSEL-UCLAF (FR) | 1994-07-26 | — | — | US | disclosed |
| US-5093337-A | SUBSTITUTED DERIVATIVES OF 20,21-DINOREBURNAMENINE, THEIR USE AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL UCLAF (FR) | 1992-03-03 | — | — | US | disclosed |