Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.42 |
| ▸ | PDE9A | O76083 | 1/20 | 0.42 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402036 | 0.90 | PPARG (0.66) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL8564506 | 0.82 | PPARG (0.62) | PPARGACHERAB9AAGTR1ALOX5AP | |
| SCHEMBL9200503 | 0.76 | PPARG (1.00) | PPARGAGTR1EDNRAAGTR2 | |
| SCHEMBL4010668 | 0.76 | PPARG (0.63) | PPARGACHEAGTR1 | |
| SCHEMBL8789971 | 0.75 | PPARG (0.65) | PPARGRAB9AAGTR1EDNRAAGTR2 | |
| SCHEMBL9543810 | 0.75 | PPARG (0.61) | PPARGACHEAGTR1DPP4AGTR2 | |
| SCHEMBL8566073 | 0.74 | PPARG (0.61) | PPARGRAB9AAGTR1ALOX5APAGTR2 | |
| SCHEMBL9197325 | 0.74 | PPARG (0.88) | PPARGAGTR1AGTR2 | |
| SCHEMBL4013891 | 0.74 | PPARG (0.61) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL4011358 | 0.74 | PPARG (0.61) | PPARGACHEAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304565-A | Angiotensin II antagonists | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-19 | — | — | US | disclosed |