SCHEMBL940206

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL939309	0.90	AURKB (0.38)	FGFR1KDRAURKAAURKBPIM1
	SCHEMBL940857	0.90	FGFR1 (0.35)	FGFR1KDRAURKAAURKBPIM1
	SCHEMBL12909145	0.90	FGFR1 (0.45)	MEN1KMT2ADDX3XFGFR1KDR
	SCHEMBL939356	0.89	POLB (0.43)	MEN1KMT2AFGFR1KDRAURKA
	SCHEMBL940272	0.89	MEN1 (0.43)	MEN1KMT2AFGFR1AURKAAURKB
	SCHEMBL940095	0.89	AURKB (0.40)	MEN1KMT2AFGFR1KDRAURKA
	SCHEMBL938901	0.89	ABL1 (0.40)	MEN1KMT2AFGFR1MTORKDR
	SCHEMBL938944	0.89	FGFR1 (0.36)	FGFR1KDRAURKAAURKBPIM1
	SCHEMBL940006	0.89	HDAC11 (0.39)	FGFR1KDRAURKAAURKBPIM1
	SCHEMBL940043	0.89	PIK3CA (0.42)	MEN1KMT2AFGFR1MTORRET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.