Hydantoin

Hydantoin

SCHEMBL9402299

CC1NC(=O)NC1=O.O=C1CNC(=O)N1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.65
BRPF1 P55201 1/20 0.36
CREBBP Q92793 1/20 0.36
CRBN Q96SW2 2/20 0.34
GSK3B P49841 1/20 0.34
ALDH1A1 P00352 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6100849 0.81
SCHEMBL21767 0.81
SCHEMBL8110002 0.81
SCHEMBL28285707 0.79
Hydantoin SCHEMBL10578146 0.78
Hydantoin SCHEMBL9798274 0.76
Hydantoin SCHEMBL27690 0.76
Hydantoin SCHEMBL27705088 0.76 CRBN (0.52) CRBNALDH1A1TDP1
Hydantoin SCHEMBL7285865 0.76
Hydantoin SCHEMBL1902842 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE34768-E Having N-heterocyclic chain extending groups, also with polyfunctional and bromine-containing epoxy resins, curing agents and accelerators, for fireproof, heat resistant, nondeforming printed circuits INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1994-10-25 US disclosed
US-5130407-A Modified epoxy resins for printed circuits and electronics INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1992-07-14 US disclosed
US-5006615-A Printed circuit INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1991-04-09 US disclosed