SCHEMBL9402808

SCHEMBL9402808

CC=CC(=O)OCC[Si](OCCC)(OCCC)OCCC

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.46
ATM Q13315 1/20 0.44
APP P05067 6/20 0.38
ALOX5 P09917 1/20 0.37
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
GSTP1 P09211 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL72842 0.90 ATM (0.50) HCAR2ATMAPPALOX5MAPT
SCHEMBL9402684 0.90 ATM (0.55) HCAR2ATMAPPALOX5MAPT
SCHEMBL845291 0.88 ATM (0.41) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL9402974 0.85 HCAR2 (0.44) HCAR2ATMAPPALOX5MAPT
SCHEMBL27869559 0.83 HCAR2 (0.43) HCAR2ATMAPPALOX5MAPT
SCHEMBL72365 0.82 ATM (0.58) HCAR2ATMAPPMAPTRAB9A
SCHEMBL182849 0.81
SCHEMBL182848 0.81
SCHEMBL16522478 0.81
SCHEMBL15405300 0.81 HCAR2 (0.53) HCAR2ATMAPPMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101226329-B Radiation sensitive resin composition, laminated insulating film, micro lens and preparation method thereof JSR CORP 2012-09-05 CN disclosed
US-5332779-A Polymerizable silica sol, adamantane derivative for use in the sol and cured resin prepared using the same KAWASAKI STEEL CORPORATION (JP) 1994-07-26 US disclosed
EP-0460560-A2 Polymerizable silica sol, adamantane derivative for use in the sol and cured resin prepared using the same KAWASAKI STEEL CORPORATION (JP) 1991-12-11 EP disclosed