Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 10/20 | 0.64 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.55 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402749 | 1.00 | PTPN11 (0.64) | PTPN11FOLH1S1PR3PTPN1PTPN6 | |
| SCHEMBL9402747 | 1.00 | PTPN11 (0.64) | PTPN11FOLH1S1PR3PTPN1PTPN6 | |
| Hydrochloric Acid SCHEMBL9402534 | 0.99 | PTPN11 (0.62) | PTPN11FOLH1S1PR3PTPN1PTPN6 | |
| Hydrochloric Acid SCHEMBL9402715 | 0.99 | PTPN11 (0.62) | PTPN11FOLH1S1PR3PTPN1PTPN6 | |
| SCHEMBL8659844 | 0.96 | FOLH1 (0.59) | PTPN11FOLH1TSHR | |
| SCHEMBL9323966 | 0.94 | PTPN11 (0.60) | PTPN11S1PR3PTPN1PTPN6PLK1 | |
| SCHEMBL22438999 | 0.91 | PTPN11 (0.62) | PTPN11PLK1TP53TSHR | |
| SCHEMBL22438896 | 0.91 | PTPN11 (0.62) | PTPN11PLK1TP53TSHR | |
| SCHEMBL9402635 | 0.91 | FOLH1 (0.59) | PTPN11FOLH1 | |
| SCHEMBL9402708 | 0.90 | PTPN11 (0.55) | PTPN11TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298652-A | N-substituted glycines, inhibitors of phospholipase A2 | HOFFMANN-LA ROCHE INC. (US) | 1994-03-29 | — | — | US | disclosed |