Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9404133 | 1.00 | MAPT (0.48) | MAPTALDH1A1HPGDTP53L3MBTL1 | |
| SCHEMBL11011008 | 1.00 | MAPT (0.48) | MAPTALDH1A1HPGDTP53L3MBTL1 | |
| SCHEMBL1416929 | 0.77 | MAPT (0.52) | MAPTALDH1A1HPGDTP53L3MBTL1 | |
| SCHEMBL8402032 | 0.77 | — | — | |
| SCHEMBL8537626 | 0.77 | — | — | |
| SCHEMBL11965678 | 0.76 | MAPT (0.50) | MAPTALDH1A1HPGDTP53L3MBTL1 | |
| SCHEMBL11009383 | 0.75 | IDO1 (0.37) | MAPTALDH1A1HPGDTP53TSHR | |
| SCHEMBL14012905 | 0.75 | IDO1 (0.37) | MAPTALDH1A1HPGDTP53TSHR | |
| SCHEMBL11009384 | 0.75 | IDO1 (0.37) | MAPTALDH1A1HPGDTP53TSHR | |
| Water SCHEMBL597798 | 0.74 | MAPK10 (0.38) | MAPTALDH1A1HPGDTP53L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6192245-A | — | — | None | — | — | JP | disclosed |
| JP-H06192245-A | PRODUCTION OF ISOTHIAZOLONE DERIVATIVE | NIPPON NOHYAKU CO LTD | 1994-07-12 | — | — | JP | disclosed |
| US-4542140-A | ANTIULCER, ANTISECRETORY, GASTROINTESTINAL DISORDERS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1985-09-17 | — | — | US | disclosed |