Oxalic Acid

Oxalic Acid

SCHEMBL9404516

C1CC1c1noc(C2CN3CCC2CC3)n1.O=C(O)C(=O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1SLC6A4

The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.48
CHRM1 P11229 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9451960 0.92 CHRM2 (0.55) CHRM2CHRM1
Hydrochloric Acid SCHEMBL10518010 0.90 CHRM2 (0.54) CHRM2CHRM1
SCHEMBL24434494 0.86 CHRM2 (0.52) CHRM2CHRM1
Fumaric Acid SCHEMBL10441420 0.85 CHRM2 (0.53) CHRM2CHRM1
Maleic Acid SCHEMBL9651786 0.85 CHRM2 (0.53) CHRM2CHRM1
Fumaric Acid SCHEMBL9651789 0.85 CHRM2 (0.53) CHRM2CHRM1
Hydrochloric Acid SCHEMBL9724734 0.83 CHRM2 (0.64) CHRM2CHRM1
Hydrochloric Acid SCHEMBL9653117 0.83 CHRM2 (0.64) CHRM2CHRM1
Oxalic Acid SCHEMBL9404396 0.79 CHRM2 (0.49) CHRM2CHRM1
Oxalic Acid SCHEMBL9724653 0.79 CHRM2 (0.49) CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5356912-A 3-(5-isoxazolyl)-1-methyl-1,2,3,6-tetrahydropyridine useful for treating Alzheimer's disease NOVO NORDISK A/S (DK) 1994-10-18 US disclosed
US-5262427-A Cognition activators for Alzheimer*s disease NOVO NORDISK A/S (DK) 1993-11-16 US disclosed
EP-0316718-B1 AZACYCLIC COMPOUNDS AND THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1993-09-15 EP disclosed
EP-0316718-A2 Azacyclic compounds and their preparation and use NOVO NORDISK A/S (DK) 1989-05-24 EP disclosed