Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778540 | 0.85 | MAPT (0.56) | TDP1TSHRCYP2C19CYP3A4MAPT | |
| SCHEMBL114583 | 0.84 | CES1 (0.58) | TDP1TSHRCYP2C19CYP3A4MAPT | |
| SCHEMBL523842 | 0.84 | CES1 (0.58) | TDP1TSHRCYP2C19CYP3A4MAPT | |
| SCHEMBL183462 | 0.84 | CES1 (0.58) | TDP1TSHRCYP2C19CYP3A4MAPT | |
| SCHEMBL28198887 | 0.81 | TSHR (0.52) | TDP1TSHRCYP2C19CYP3A4MAPT | |
| SCHEMBL8398051 | 0.81 | CYP2C19 (0.52) | TDP1TSHRCYP2C19CYP3A4MAPT | |
| SCHEMBL8397878 | 0.81 | CYP2C19 (0.52) | TDP1TSHRCYP2C19CYP3A4MAPT | |
| SCHEMBL7567511 | 0.79 | TDP1 (0.62) | TDP1TSHRCYP2C19CYP3A4MAPT | |
| SCHEMBL29290730 | 0.79 | CES1 (0.52) | TDP1TSHRCYP2C19CYP3A4MAPT | |
| SCHEMBL10497226 | 0.79 | TDP1 (0.62) | TDP1TSHRCYP2C19CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6199759-A | — | — | None | — | — | JP | disclosed |
| JP-H06199759-A | PREPARATION OF PHENYLACETIC ACID DERIVATIVE | CIBA GEIGY AG | 1994-07-19 | — | — | JP | disclosed |