SCHEMBL9405344

SCHEMBL9405344

COc1ccccc1CP(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.48
TAAR1 Q96RJ0 1/20 0.48
CHRM2 P08172 3/20 0.47
CHRM1 P11229 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
HTT P42858 1/20 0.46
ALDH1A1 P00352 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
ATM Q13315 1/20 0.45
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA4 P22748 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
ABCB1 P08183 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27966988 0.85 CHRM2 (0.40) IDO1TAAR1CHRM2CHRM1L3MBTL1
SCHEMBL5398197 0.85 ABCB1 (0.40) IDO1TAAR1CHRM2CHRM1L3MBTL1
SCHEMBL14604155 0.85 CHRM2 (0.40) IDO1TAAR1CHRM2CHRM1L3MBTL1
SCHEMBL9405346 0.85 IDO1 (0.48) IDO1TAAR1CHRM2CHRM1L3MBTL1
SCHEMBL14604233 0.84 IDO1 (0.39) IDO1TAAR1CHRM2CHRM1L3MBTL1
SCHEMBL15710319 0.84 CHRM2 (0.40) IDO1TAAR1CHRM2CHRM1L3MBTL1
SCHEMBL27967178 0.84 IDO1 (0.39) IDO1TAAR1CHRM2CHRM1L3MBTL1
SCHEMBL5401691 0.84 HRH1 (0.40) CHRM1
SCHEMBL12050455 0.84 IDO1 (0.41) IDO1TAAR1CHRM2CHRM1L3MBTL1
SCHEMBL3310327 0.83 IDO1 (0.47) IDO1TAAR1CHRM2CHRM1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108339571-A P- chiral source organic phosphorus compounds 国家科学研究中心 2018-07-31 CN disclosed
CN-103797020-B P-chirality source organic phosphorus compound 国家科学研究中心 2018-01-30 CN disclosed
EP-0160824-B2 Reaction product of olefinically unsaturated compounds with active hydrogen compounds, process for their preparation and 2-component coating systems based thereon HOECHST AG (DE) 1994-08-03 EP disclosed
EP-0224158-B1 Hardenable mixture based on olefinically unsaturated compounds and active hydrogen-containing compounds. HOECHST AG (DE) 1993-12-22 EP disclosed
US-5169979-A Cures rapidly at low temperatures; surface coatings HOECHST AG (DE) 1992-12-08 US disclosed
US-5084536-A Reaction product of olefinically unsaturated compounds with compounds containing active hydrogen, processes for their preparation and 2-component lacquers based thereon HOECHST AG (DE) 1992-01-28 US disclosed
EP-0310011-B1 CURING AGENT AND ITS USE HOECHST AKTIENGESELLSCHAFT (DE) 1991-07-24 EP disclosed
US-4871822-A Reaction product of olefinically unsaturated compounds with compounds containing active hydrogen, processes for their preparation and 2-component lacquers based thereon HOE 85/F O36J HOECHST AG (DE) 1989-10-03 US disclosed
EP-0160824-B1 REACTION PRODUCT OF OLEFINICALLY UNSATURATED COMPOUNDS WITH ACTIVE HYDROGEN COMPOUNDS, PROCESS FOR THEIR PREPARATION AND 2-COMPONENT COATING SYSTEMS BASED THEREON HOECHST AKTIENGESELLSCHAFT (DE) 1989-09-06 EP disclosed
EP-0310011-A1 Curing agent and its use HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-05 EP disclosed
EP-0224158-A2 Hardenable mixture based on olefinically unsaturated compounds and active hydrogen-containing compounds. HOECHST AKTIENGESELLSCHAFT (DE) 1987-06-03 EP disclosed
EP-0160824-A1 Reaction product of olefinically unsaturated compounds with active hydrogen compounds, process for their preparation and 2-component coating systems based thereon HOECHST AKTIENGESELLSCHAFT (DE) 1985-11-13 EP disclosed