SCHEMBL9405697

SCHEMBL9405697

CCCCCC[C@H](C)C(=O)c1ccc(-c2ccc(OC)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 4/20 0.49
MEN1 O00255 1/20 0.49
CYP2D6 P10635 1/20 0.49
HTT P42858 1/20 0.49
KMT2A Q03164 1/20 0.49
SLC6A2 P23975 1/20 0.47
SLC6A4 P31645 1/20 0.47
SLC6A3 Q01959 1/20 0.47
MMP9 P14780 4/20 0.46
MMP13 P45452 4/20 0.46
ADAM17 P78536 4/20 0.46
MMP1 P03956 4/20 0.46
TAS1R3 Q7RTX0 1/20 0.46
TAS1R1 Q7RTX1 1/20 0.46
HDAC3 O15379 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC2 Q92769 1/20 0.45
MMP2 P08253 1/20 0.44
MMP3 P08254 1/20 0.44
PNLIP P16233 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9405700 1.00 RARB (0.49) RARBMEN1CYP2D6HTTKMT2A
SCHEMBL27457534 0.96 HTT (0.52) MEN1CYP2D6HTTKMT2ASLC6A2
SCHEMBL9440242 0.96 HTT (0.52) MEN1CYP2D6HTTKMT2ASLC6A2
Hydrochloric Acid SCHEMBL30725888 0.93 HTT (0.56) MEN1CYP2D6HTTKMT2ASLC6A2
SCHEMBL9325412 0.84 KMT2A (0.48) RARBMEN1CYP2D6KMT2ASLC6A2
SCHEMBL9324332 0.84 HSD17B3 (0.51) RARBMEN1CYP2D6KMT2ASLC6A2
SCHEMBL9717228 0.84 NPC1 (0.51) RARBMEN1HTTKMT2AMMP9
SCHEMBL9405582 0.84 HSD17B3 (0.51) RARBMEN1CYP2D6KMT2ASLC6A2
SCHEMBL9717247 0.84 RARB (0.59) RARBMEN1KMT2A
SCHEMBL28718619 0.84 SLC6A2 (0.58) MEN1CYP2D6HTTKMT2ASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0402110-B1 Optical active compounds and liquid crystal compositions containing such compounds WAKO PURE CHEM IND LTD (JP) 1994-12-14 EP disclosed
US-5128062-A OPTICALLY ACTIVE COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING SUCH COMPOUNDS WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1992-07-07 US disclosed
EP-0402110-A1 Optical active compounds and liquid crystal compositions containing such compounds WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1990-12-12 EP disclosed