Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9405806 | 1.00 | SPHK1 (0.43) | SPHK1SPHK2CYP2C9ALDH1A1LMNA | |
| SCHEMBL22277577 | 0.97 | SPHK1 (0.40) | SPHK1SPHK2CYP2C9 | |
| SCHEMBL9405770 | 0.92 | CYP2C9 (0.41) | SPHK1SPHK2CYP2C9ALDH1A1LMNA | |
| SCHEMBL9405767 | 0.92 | CYP2C9 (0.41) | SPHK1SPHK2CYP2C9ALDH1A1LMNA | |
| SCHEMBL22277311 | 0.92 | SPHK1 (0.40) | SPHK1SPHK2 | |
| SCHEMBL22277306 | 0.92 | SPHK1 (0.40) | SPHK1SPHK2CYP2C9 | |
| SCHEMBL13235314 | 0.92 | SPHK1 (0.40) | SPHK1SPHK2CYP2C9ALDH1A1LMNA | |
| SCHEMBL13235354 | 0.92 | SPHK1 (0.40) | SPHK1SPHK2CYP2C9ALDH1A1LMNA | |
| SCHEMBL13026085 | 0.91 | SPHK1 (0.40) | SPHK1SPHK2CYP2C9ALDH1A1LMNA | |
| SCHEMBL12032182 | 0.90 | SPHK1 (0.37) | SPHK1SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5279764-A | Dihalogenobenzene derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-01-18 | — | — | US | disclosed |