Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 5/20 | 0.36 |
| ▸ | HTR2B | P41595 | 5/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9405905 | 1.00 | FFAR1 (0.39) | FFAR1HTR2CHTR2BHTR2ARIPK1 | |
| SCHEMBL9405904 | 1.00 | FFAR1 (0.39) | FFAR1HTR2CHTR2BHTR2ARIPK1 | |
| SCHEMBL24170503 | 0.94 | HTR2C (0.40) | HTR2CHTR2BHTR2ARIPK1BRD4 | |
| SCHEMBL14391042 | 0.94 | HTR2C (0.40) | HTR2CHTR2BHTR2ARIPK1BRD4 | |
| SCHEMBL12366408 | 0.91 | HTR2A (0.38) | HTR2CHTR2BHTR2ARIPK1BRD4 | |
| SCHEMBL9406086 | 0.89 | FFAR1 (0.38) | FFAR1HTR2CHTR2BHTR2ARIPK1 | |
| SCHEMBL9406082 | 0.89 | FFAR1 (0.38) | FFAR1HTR2CHTR2BHTR2ARIPK1 | |
| SCHEMBL9406078 | 0.89 | FFAR1 (0.38) | FFAR1HTR2CHTR2BHTR2ARIPK1 | |
| SCHEMBL9561956 | 0.88 | PDE4B (0.39) | HTR2CHTR2BHTR2ARIPK1PDE4A | |
| SCHEMBL9561951 | 0.88 | PDE4B (0.39) | HTR2CHTR2BHTR2ARIPK1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5279764-A | Dihalogenobenzene derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-01-18 | — | — | US | disclosed |