SCHEMBL9406014

SCHEMBL9406014

CCCCCCCCOc1ccc([C@H]2CC[C@H](CCC)CC2)c(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
SCN9A Q15858 1/20 0.34
CYP2C9 P11712 1/20 0.34
PLA2G2D Q9UNK4 1/20 0.34
PPARG P37231 1/20 0.34
SMPD1 P17405 3/20 0.33
ESR1 P03372 2/20 0.33
THRA P10827 1/20 0.33
THRB P10828 1/20 0.33
HTR1D P28221 1/20 0.33
HTR1B P28222 1/20 0.33
FPR2 P25090 1/20 0.33
S1PR5 Q9H228 2/20 0.33
S1PR1 P21453 1/20 0.33
PTPN1 P18031 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9406023 1.00 CNR1 (0.35) CNR1CNR2SCN9ACYP2C9PLA2G2D
SCHEMBL9630413 0.99 CNR1 (0.35) CNR1CNR2SCN9ACYP2C9PLA2G2D
SCHEMBL9630415 0.99 CNR1 (0.35) CNR1CNR2SCN9ACYP2C9PLA2G2D
SCHEMBL9631624 0.99 SCN9A (0.35) CNR1CNR2SCN9ACYP2C9PLA2G2D
SCHEMBL9631628 0.99 SCN9A (0.35) CNR1CNR2SCN9ACYP2C9PLA2G2D
SCHEMBL9632575 0.97 SCN9A (0.34) CNR1CNR2SCN9ACYP2C9PLA2G2D
SCHEMBL9632579 0.97 SCN9A (0.34) CNR1CNR2SCN9ACYP2C9PLA2G2D
SCHEMBL17900180 0.97 CYP2C9 (0.35) CNR1CNR2SCN9ACYP2C9PPARG
SCHEMBL19985184 0.96 CNR1 (0.34) CNR1CNR2SCN9ACYP2C9PLA2G2D
SCHEMBL9630574 0.96 CNR1 (0.34) CNR1CNR2SCN9ACYP2C9PLA2G2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5279764-A Dihalogenobenzene derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-01-18 US disclosed