Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.39 |
| ▸ | RARB | P10826 | 3/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9406094 | 1.00 | CNR2 (0.39) | CNR2RARBPTPN11NR5A1CNR1 | |
| SCHEMBL9405867 | 0.98 | CNR2 (0.39) | CNR2RARBPTPN11NR5A1CNR1 | |
| SCHEMBL9405862 | 0.98 | CNR2 (0.39) | CNR2RARBPTPN11NR5A1CNR1 | |
| SCHEMBL17084298 | 0.97 | CNR2 (0.40) | CNR2RARBPTPN11NR5A1CNR1 | |
| SCHEMBL9405897 | 0.97 | CNR2 (0.40) | CNR2RARBPTPN11NR5A1CNR1 | |
| SCHEMBL16187782 | 0.97 | CNR2 (0.40) | CNR2RARBPTPN11NR5A1CNR1 | |
| SCHEMBL9406195 | 0.97 | CNR2 (0.40) | CNR2RARBPTPN11NR5A1CNR1 | |
| SCHEMBL16187778 | 0.97 | CNR2 (0.40) | CNR2RARBPTPN11NR5A1CNR1 | |
| SCHEMBL9406191 | 0.97 | CNR2 (0.40) | CNR2RARBPTPN11NR5A1CNR1 | |
| SCHEMBL9405891 | 0.97 | CNR2 (0.40) | CNR2RARBPTPN11NR5A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5279764-A | Dihalogenobenzene derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-01-18 | — | — | US | disclosed |