Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 17/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9406145 | 1.00 | CYP2C9 (0.41) | CYP2C9OPRL1ALDH1A1LMNAMAPT | |
| SCHEMBL2905645 | 0.95 | OPRL1 (0.39) | CYP2C9OPRL1ALDH1A1LMNAMAPT | |
| SCHEMBL2905649 | 0.95 | OPRL1 (0.39) | CYP2C9OPRL1ALDH1A1LMNAMAPT | |
| SCHEMBL2905643 | 0.95 | OPRL1 (0.39) | CYP2C9OPRL1ALDH1A1LMNAMAPT | |
| SCHEMBL14494545 | 0.95 | OPRL1 (0.39) | CYP2C9OPRL1ALDH1A1LMNAMAPT | |
| SCHEMBL9405739 | 0.90 | OPRL1 (0.39) | CYP2C9OPRL1MAPTMEN1MAPK1 | |
| SCHEMBL9405734 | 0.90 | OPRL1 (0.39) | CYP2C9OPRL1MAPTMEN1MAPK1 | |
| SCHEMBL9406020 | 0.89 | GAA (0.39) | OPRL1MAPTMEN1KMT2A | |
| SCHEMBL9406012 | 0.89 | GAA (0.39) | OPRL1MAPTMEN1KMT2A | |
| SCHEMBL716244 | 0.89 | OPRL1 (0.45) | CYP2C9OPRL1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5279764-A | Dihalogenobenzene derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-01-18 | — | — | US | disclosed |