Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.34 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9406209 | 1.00 | HTR2A (0.36) | HTR2AHTR2CHTR2BRIPK1GRM2 | |
| SCHEMBL9406115 | 1.00 | HTR2A (0.36) | HTR2AHTR2CHTR2BRIPK1GRM2 | |
| SCHEMBL9406204 | 1.00 | HTR2A (0.36) | HTR2AHTR2CHTR2BRIPK1GRM2 | |
| SCHEMBL9406347 | 1.00 | HTR2A (0.36) | HTR2AHTR2CHTR2BRIPK1GRM2 | |
| SCHEMBL9406120 | 1.00 | HTR2A (0.36) | HTR2AHTR2CHTR2BRIPK1GRM2 | |
| SCHEMBL9406449 | 0.95 | HTR2A (0.37) | HTR2AHTR2CHTR2BRIPK1GRM2 | |
| SCHEMBL9406444 | 0.95 | HTR2A (0.37) | HTR2AHTR2CHTR2BRIPK1GRM2 | |
| SCHEMBL8932793 | 0.93 | GRM2 (0.35) | HTR2AHTR2CHTR2BRIPK1GRM2 | |
| SCHEMBL9405874 | 0.90 | HTR2A (0.38) | HTR2AHTR2CHTR2BRIPK1SSTR5 | |
| SCHEMBL9405871 | 0.90 | HTR2A (0.38) | HTR2AHTR2CHTR2BRIPK1SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5279764-A | Dihalogenobenzene derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-01-18 | — | — | US | disclosed |