1,6-Hexanediol

1,6-Hexanediol

SCHEMBL9406791

C=CC(=O)OC.CCOCC.OCCCCCCO

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.40
HPGD P15428 1/20 0.40
ALDH1A1 P00352 5/20 0.39
CYP3A4 P08684 1/20 0.39
CYP4F2 P78329 2/20 0.36
CYP4A11 Q02928 2/20 0.36
TP53 P04637 2/20 0.35
HIF1A Q16665 2/20 0.35
HSD17B10 Q99714 1/20 0.35
LMNA P02545 1/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34
ACHE P22303 6/20 0.34
THRB P10828 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid Methyl Ester SCHEMBL22263205 0.90 TSHR (0.43) TSHRHPGDALDH1A1CYP3A4TP53
1,6-Hexanediol SCHEMBL10634052 0.90 TSHR (0.46) TSHRHPGDALDH1A1CYP3A4CYP4F2
1,6-Hexanediol SCHEMBL27393515 0.90 TSHR (0.46) TSHRHPGDALDH1A1CYP3A4CYP4F2
Acrylic Acid Methyl Ester SCHEMBL28029883 0.90 TSHR (0.46) TSHRHPGDALDH1A1CYP3A4CYP4F2
Acrylic Acid Methyl Ester SCHEMBL28826944 0.90 TSHR (0.46) TSHRHPGDALDH1A1CYP3A4CYP4F2
Acrylic Acid Methyl Ester SCHEMBL9303641 0.89 TSHR (0.42) TSHRHPGDALDH1A1CYP3A4TP53
Acrylic Acid Methyl Ester SCHEMBL27334995 0.88 TSHR (0.48) TSHRHPGDALDH1A1CYP3A4CYP4F2
Acrylic Acid Methyl Ester SCHEMBL235879 0.88 TSHR (0.44) TSHRHPGDALDH1A1CYP3A4TP53
Octanol SCHEMBL27841339 0.87 TSHR (0.50) TSHRHPGDALDH1A1CYP3A4HSD17B10
Dodecanol SCHEMBL27575009 0.87 TSHR (0.50) TSHRHPGDALDH1A1CYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5292965-A Monomethoxy propoxylated glycerol DIAMOND SHAMROCK CHEMICALS COMPANY 1994-03-08 US disclosed
US-5243085-A Starting materials for improved radiation hardenable diluents DIAMOND SHAMROCK CHEMICAL CO. (US) 1993-09-07 US disclosed
US-5159119-A Monomethyl ether of trans 1,4-cyclohexanedimethylol DIAMOND SHAMROCK CHEMICALS COMPANY (US) 1992-10-27 US disclosed
EP-0222059-B1 IMPROVED RADIATION-HARDENABLE DILUENTS HENKEL CORPORATION (a Delaware corp.) (US) 1992-07-08 EP disclosed
US-5110889-A Lower alkyl ether acrylates of polyols; coatings DIAMOND SHAMROCK CHEMICAL CO. (US) 1992-05-05 US disclosed
US-5053554-A Monomethyl ether of an ethoxylated or propoxylated(2 average) neopentyl glycol; nonvolatile coating formulation; fact cure; low viscosity; shrinkage inhibition; rheology DIAMOND SHAMROCK CHEMICAL COMPANY 1991-10-01 US disclosed
US-4876384-A ALKYL ETHER ACRYLATES AND METHACRYLATES OF ALKOXYLATED AND NONALKOXYLATED POLYOLS; LOW VISCOSITY; SHRINKAGE INHIBITION DIAMOND SHAMROCK CHEMICALS CO. (US) 1989-10-24 US disclosed
EP-0222059-A2 Improved radiation-hardenable diluents HENKEL CORPORATION (a Delaware corp.) (US) 1987-05-20 EP disclosed