Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17592570 | 1.00 | MAPT (0.57) | MAPTCYP1A2POLBHPGDHTT | |
| SCHEMBL9406956 | 1.00 | MAPT (0.57) | MAPTCYP1A2POLBHPGDHTT | |
| SCHEMBL10951013 | 0.94 | MAPT (0.53) | MAPTCYP1A2POLBHPGDHTT | |
| SCHEMBL10846877 | 0.94 | MAPT (0.53) | MAPTCYP1A2POLBHPGDHTT | |
| SCHEMBL10951008 | 0.94 | MAPT (0.53) | MAPTCYP1A2POLBHPGDHTT | |
| SCHEMBL17592080 | 0.94 | MAPT (0.51) | MAPTCYP1A2POLBHPGDHTT | |
| SCHEMBL10726112 | 0.94 | MAPT (0.51) | MAPTCYP1A2POLBHPGDHTT | |
| SCHEMBL9899525 | 0.94 | MAPT (0.51) | MAPTCYP1A2POLBHPGDHTT | |
| Hydrochloric Acid SCHEMBL9341100 | 0.92 | MAPT (0.50) | MAPTCYP1A2POLBHPGDHTT | |
| Hydrochloric Acid SCHEMBL9341103 | 0.92 | MAPT (0.50) | MAPTCYP1A2POLBHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191088-B1 | AN ANTICONVULSANT COMPOUND | ROYAL HOLLOWAY & BEDFORD NEW COLLEGE (GB) | 2020-12-16 | — | — | EP | claimed |
| US-10301263-B2 | Anticonvulsant compound | ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE (GB) | 2019-05-28 | — | — | US | claimed |
| US-20170305859-A1 | An Anticonvulsant Compound | ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE (GB) | 2017-10-26 | — | — | US | claimed |
| EP-3191088-B1 | AN ANTICONVULSANT COMPOUND | ROYAL HOLLOWAY & BEDFORD NEW COLLEGE (GB) | 2020-12-16 | — | — | EP | disclosed |
| US-10301263-B2 | Anticonvulsant compound | ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE (GB) | 2019-05-28 | — | — | US | disclosed |
| US-20170305859-A1 | An Anticonvulsant Compound | ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE (GB) | 2017-10-26 | — | — | US | disclosed |
| US-5354502-A | Very large dielectric anisotropy and small birefringence | SEIKO EPSON CORPORATION (JP) | 1994-10-11 | — | — | US | disclosed |
| US-5238599-A | Low threshold voltage, low driving voltage | SEIKO EPSON CORPORATION (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0447565-A1 | 1,3-DIOXANE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | SEIKO EPSON CORPORATION (JP) | 1991-09-25 | — | — | EP | disclosed |
| EP-0400861-A1 | 1,3-dioxane derivative and liquid crystal composition incorporating the same | SEIKO EPSON CORPORATION (JP) | 1990-12-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305859-A1 | An Anticonvulsant Compound | PSEN2, BACE2, APP | MAPT 29/4885CYP1A2 279/4885POLB 3181/4885 |
| US-10301263-B2 | Anticonvulsant compound | PSEN2, BACE2, APP | MAPT 27/4885CYP1A2 230/4885POLB 3155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.