Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 8/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL315026 | 0.91 | HPGD (0.60) | HPGDPTPN2PTPN1PTPN6RECQL | |
| SCHEMBL10177908 | 0.87 | HPGD (0.54) | HPGDPTPN2PTPN1PTPN6CHRM1 | |
| SCHEMBL16823903 | 0.87 | HPGD (0.48) | HPGDPTPN2PTPN1PTPN6RECQL | |
| SCHEMBL15746875 | 0.84 | HPGD (0.56) | HPGDPTPN2PTPN1PTPN6RECQL | |
| SCHEMBL14743631 | 0.84 | HPGD (0.56) | HPGDPTPN2PTPN1PTPN6RECQL | |
| SCHEMBL316087 | 0.84 | HPGD (0.56) | HPGDPTPN2PTPN1PTPN6RECQL | |
| SCHEMBL15487760 | 0.84 | HPGD (0.56) | HPGDPTPN2PTPN1PTPN6CHRM1 | |
| SCHEMBL4161964 | 0.82 | HPGD (0.50) | HPGDPTPN2PTPN1PTPN6CHRM1 | |
| SCHEMBL10177875 | 0.82 | HPGD (0.51) | HPGDPTPN2PTPN1PTPN6RECQL | |
| SCHEMBL10177922 | 0.82 | HPGD (0.51) | HPGDPTPN2PTPN1PTPN6RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0608858-A1 | 5-Membered heterocycles as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-08-03 | — | — | EP | disclosed |